Master Thesis Project in Neuroimmunology and Data Science

20.01.2026, Abschlussarbeiten, Bachelor- und Masterarbeiten

The research groups Data Science in Neurology and Immune-Glia Interactions in CNS Disorders at the TUM University Hospital rechts der Isar are offering a Master’s thesis project starting immediately.

Project Aim:
To establish a prime editing pipeline for human cell populations in order to investigate how genetic risk variants associated with multiple sclerosis susceptibility and severity affect gene expression across different cell types, with a particular focus on adaptive and innate immune cells.

Your Tasks:
• Molecular cloning workflows (including plasmid purification and modification)
• Production of lentiviral vectors
• Isolation, cultivation, and genetic manipulation of primary human T cells

Preferred Qualifications:
• Prior experience in molecular cloning
• Experience with cultivation of human T cells
• Experience with CRISPR-based genome engineering

What We Expect:
• High level of commitment and reliability
• Ability to work collaboratively in a collegial and productive environment

We look forward to receiving your application!

Please send your documents electronically to ali.afzali@tum.de.

Neurologische Klinik und Poliklinik
AG Data Science in Neurology
PD Dr. med. Christiane Gasperi
Universitätsklinikum rechts der Isar der TU München
Ismaninger Str. 22, 81675 München
https://neurologie.mri.tum.de/de/forschung/data-science-der-neurologie

Institut für Experimentelle Neuroimmunologie (ENI)
AG Immune-Glia Interactions in CNS Disorders
PD Dr. med. Ali Maisam Afzali
Universitätsklinikum rechts der Isar der TU München
Ismaninger Str. 22, 81675 München
https://eni.mh.tum.de/immune-glia/

Kontakt: ali.afzali@tum.de

Mehr Information

https://eni.mh.tum.de/immune-glia/